Talk:Common gamma chain

Molecular Biology: Genetics / MCB / Cell Signaling

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IL2RG

IL2RG is an old term for this protein. It will likely stick around for a while, but because this cytokine receptor is common to at least 6 cytokines, it is no longer considered just "interleukin-2 receptor". The preferred article should be Common gamma chain, Cytokine receptor common gamma chain or Common γ chain.--ZayZayEM (talk) 06:05, 26 November 2007 (UTC)[reply]

Okay, understanding a little better. IL2RG is a human gene that codes for "cytokine receptor common γ chain" which is a protein.

Should this article still be referring to IL2RG or Interleukin-2 Receptor gamma-chain, when this is an out-dated term for the gene?

I do not think so, but can understand how purging the term may result in confusion.--ZayZayEM (talk) 01:27, 27 October 2008 (UTC)[reply]

Gene/protein name

Hi. I agree that the nomenclature is rather confusing. However the name IL2RG is definitely not out-of-date since it is the currently accepted official Human Genome Organisation gene name (see IL2RG). There are a lot of names one could call this gene/protein including:

interleukin 2 receptor, gamma (IL2RG)
interleukin receptor, common gamma chain
interleukin receptor, gamma-c
CD132 antigen (cluster of differentiation 132)

I would suggest that we rename this article as "interleukin receptor, common gamma chain", with the lead reading:

Interleukin receptor, common gamma chain also known as interleukin 2 receptor, gamma (IL2RG) or CD132 (cluster of differentiation 132) is a protein which in humans is encoded by the IL2RG gene.

Also I agree that the contents of this article be merged with the IL2RG article since the subject matter of both articles deals with the same gene/protein. Does this sound reasonable? Cheers. Boghog2 (talk) 12:34, 18 November 2008 (UTC)[reply]